Line conventional size cupcake pan with paper liners. Mix cake according to manufacturer’s instructions then use a #16 blue scoop to deposit 1.5 oz. batter into each cavity. Bake at 350°F until cupcakes spring back lightly when touched. Let cool completely.
Place buttercreme in a piping bag fitted with an open French star tip. Using a 1-inch round cutter, cut the center out of each cupcake. Fill cavity with pumpkin cream cheese filling. Pipe a swirl of buttercreme on top of cupcakes and decorate with sprinkles.
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